NUGENOB – Tecnological Implementation Plan - Presented on CORDIS
The NUGENOB TIP on CORDIS
Selected Offers from the NUGENOB TIP on CORDIS
http://cordis.europa.eu/fetch?CALLER=OFFR_TM_EN&QM_EN_DOMAIN=&QM_EN_AREA=&QZ_WEBSRCH=nugenob
Original Papers Published in Peer Reviewed
Journals
Arvidsson E et al. Effects of different hypocaloric diets on protein secretion from adipose tissue of obese women. Diabetes 2004 Aug; 53 (8): 1966-71 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=15277374
Blaak EE et al. Fat oxidation before and after a high fat load in the obese insulin-resistant state. J Clin Endocrinol Metab. 2006 Apr;91(4):1462-9. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16449343
Boutin et al. GAD2 on chromosome 10p12 is a candidate gene for human obesity. PloS biology 2003.
http://www.plosbiology.org/plosonline/?request=index-html
Dalgaard LT et al. Mutational analysis of the UCP2 core promoter and relationships of variants with obesity. Obes Res 2003;11:1420-1427.
http://www.obesityresearch.org/cgi/reprint/11/11/1420.pdf
Dahlman et al. Changes in adipose tissue gene expression with energy-restricted diets in obese women. Am J Clin Nutr. 2005 Jun;81(6):1275-85. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=159418
Draper N et al. Association studies between microsatellite markers within the gene encoding human 11beta-hydroxysteroid dehydrogenase type 1 and body mass index, waist to hip ratio, and glucocorticoid metabolism. J Clin Endocrinol Metab 2002; 87(11):4984-4990. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=12414862
Linder et al. Differentially expressed genes in visceral or subcutaneous adipose tissue of obese men and women. Journal of Lipid Research 45:148-54, 2004. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=14563828
Meyre et al. A genome-wide scan for childhood obesity-associated traits in French families shows significant linkage on chromosome 6q22.31-q23.2. Diabetes. 2004 Mar;53(3):803-811. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=14988267
Petersen et al. Randomized, multi-center trial of two hypo-energetic diets in obese subjects: high- versus low-fat content. Int J Obes (Lond). 2006 Mar;30(3):552-60 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16331300
Rubingh CM et al. Assessing the performance of statistical validation tools for megavariate metabolomics. Metabolomics 2006;2:53-61. http://www.springerlink.com/content/06pm2745514831v0/?p=db5275b575c44208978ad5d7534fe885&pi=0
Santos JL et al. Genotype-by-nutrient interactions assessed in European obese women : A case-only study. Eur J Nutr 2006 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Citation&list_uids=17080261
Sørensen TIA et al. (2006) Genetic polymorphisms and weight loss in obesity: A randomised trial of hypo-energetic high- versus low-fat diets. PLoS Clin Trials 1(2): e12. DOI: http://clinicaltrials.plosjournals.org/perlserv/?request=get-document&doi=10.1371/journal.pctr.0010012
Tehard et al. Comparison of two physical activity questionnaires in obese subjects: the NUGENOB study.
Med Sci Sports Exerc. 2005 Sep;37(9):1535-41. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16177606
Viguerie N et al. Adipose tissue gene expression in obese subjects during low-fat and high-fat hypocaloric diets. Diabetologia. 2005 48:123-131 http://springerlink.metapress.com/link.asp?id=32rjeykdumlqp6k0
Yanagisawa et al. The FOXC2 -512C>T variant is associated with hypertriglyceridemia and elevated serum C-peptide in glucose tolerant subjects. Diabetologia, 2003 Nov;46(11):1576-80. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=14530861
Presentation of NUGENOB in scientific books etc
The Nugenob project as well as the key aspects of nutrient- gene interaction in human obesity of relevance to this topic is presented in Chapter 2 in 'Food, diet and obesity'and in Chapter 10 in 'Functional foods, ageing and degenerative disease'
2 Nutrient–gene interactions contributing to the development of obesity
C Verdich, Danish Epidemiology Science Centre, K Clement, INSERM, France and T Sorenson, Copenhagen University Hospital, Denmark
- Introduction
- Genetic influences on obesity
- Nutrient-sensitive genes
- Interactions between genetic background and diets
- Managing obesity: dietary and other strategies
- Future trends
- Sources of further information and advice
- References
in: Food, diet and obesity: Woodhead Publishing Ltd, Cambridge. 2005: pp17-57; ISBN1855739585.
10 Nutrient-gene interactions in the control of obesity
C Verdich and T I A Sorensen, Copenhagen University Hospital, Denmark and K Clement, INSERM, France
- Introduction
- Genetic influences on obesity
- Nutrient-sensitive genes
- Nutrient-gene interaction and the development of obesity
- Managing obesity: dietary and other strategies
- Future trends
- Sources of further information
- Reference
in: Functional foods, ageing and degenerative disease':
Woodhead Publishing Ltd, Cambridge. 2004: pp223-259; ISBN1855737256
Printed articles in newspapers and popular magazines
NYH:S 2001 No3:pp22-23.
"På jagt efter årsagen til fedme"/"Searching for
the mechanisms behind Obesity"
(magazine for Copenhagen Hospital Corporation, Denmark)
Annual Report for the University of Copenhagen, 2001 pp24-25 (Spring 2002)
"Fedmeepidemiens trussel "/"The impending obesity epidemic"
(Danish and English. Also presented on the internet)
Copenhagen University: Newsletter on health related sciences:
Helse 2002 No9:pp61-62 (September 2002)
"Fedmens gåde"/"The enigma of Obesity"
(Danish health magazine for consumers)
Vital 2002 No 4 pp 25 (December 2002)
"Forskning i fedmegener"/ "Research on obesity genes"
(Magazine on prevention publiced by the Danish National Board of Health)
Oral presentations (with or without abstract)
This section is no longer being updated.
40thAniversary at Institute of Preventive Medicine.
Copenhagen 10th-11th of October 2002
Titel: NUGENOB: a European joined action
Presenter: Camilla Verdich/Partner 1/Copenhagen
Abstract: none
The national conference of Czech Society of Obesity 2002,
Carlsbad on 25th October 2002
Title: European study NUGENOB.
Presenter P. Sramkova,
Abstract: none
The NUGENOB project was presented in relation to the H3 course of the XXII Summer Course_ XV European Courses of the University of the Basque Country in San Sebastian: "Nutrición, Genes y Obesidad", Directed by Ph.D. Alfredo Martinz [No abstract].
the NUGENOB project and preliminary results related to candidate genes and the weight loss intervention was presented by Professor Philippe Froguel and Professor Arne Astrup at the Copenhagen Obesity Symposium 2003, 18th-21st of September 2003 [No abstract].
The NUGENOB project and preliminary results of the weight loss intervention was presented by Professor Arne Astrup in the lecture "Should the food pyramid be inverted" at the NAASO/ADA annual meeting, Fort Lauderdale, Fl. the 13th of October 2003.
The NUGENOB project will be presented at the annual meeting of the Danish Society of Obesity Research (DSAF), October 2003:
Martin Petersen et al: A randomised trial comparing two hypocaloric diets with different fat and carbohydrate contents, in European obese subjects: random_trial_comparing_hypocaloric_diets.doc
Camilla Verdich et al: Changes in body composition during weight loss in obese subjects: a comparison of bioimpedance vs Dual Energy X-ray Absorptiometry: DSAF_DEXA_BIA_Verdich.doc
At the meeting for The Association for the Study of Obesity (UK)- 20th of November
2003- Moira Taylor presented the overall results of the weight loss intervention,
presenting only results that had already been presented at the ECO in Helsinki.
http://www.aso.org.uk/apps/briefings/briefings_content.asp?HeaderId=440
Websites presenting information on NUGENOB click here